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24/10/2017
Toxicity:
5 patients with grade 3 unilateral optic
neuropathy
2 patients with grade 4 bilateral optic
neuropathy
13 patients with Grade 3 temporal lobe
necrosis
1 with cerebellar necrosis
1 grade 4 spinal cord necrosis
3 patients with grade 3 unilateral hearing loss.