2182-2183 / 2437
213 patients
Whole brain radiotherapy following radiosurgery
NCCTG N0574 (Alliance) trial
randomise
1 - 3 brain metastases
radiosurgery &
whole brain radiotherapy
radiosurgery alone
Brown
et al 2016 JAMA, 316, 401-409
1
∘
endpoint:
cognitive progression after treatment
2
∘
endpoint
survival
Cognitive progression
cognitive function tests - drop in 1SD in one test