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Clinical case
History of present illness:
40 year old woman
2 generalized
epileptic seizures in july 2000
Past Medical History:
Several head traumas
Hypothyroidism
Migraine
Initial CT-SCAN:
Ipodense lesion in the left frontal lobe (2 cm) w/o contrast enhancement:
attributed to a scar
initiate of carbamazepine
Persistence of epileptic seizure:
Minimal increase of MRI abnormality without contrast enhancement, with
features of low grade glioma
Therapy
Biopsy at that time consistent with Anaplastic astrocytoma WHO
III, no Molecular Biology
GTR + RT 66Gy/2Gy daily fractions (2000) (for MRC trial)