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How large should be the margin? Which
technique should be used?
•
Several series analyzed the pattern of failure after
radiotherapy for LGG
•
In the NCCTG 86-72-51 trial 92% of the failures occurred
in the treatment field, 3% within 2cm and 5% more than 2
cm
•
Radiosurgery remains investigational but margins may be
reduced
•
Protons may reduce the integral dose and can result in
reduction of late toxicity