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Treatment
IDH mutation status
High risk Low
Grade Glioma
IDHwt
Combined
treatment
modality,
novel
treatment
approaches
IDHmt
1p/19q
codel
Single modality
treatment: TMZ
alone or RT
alone
1p/19q
noncodel
Combined
treatment
with RT +/-
CHX
Treatment algorithm based on molecular
marker
Courtesy of B. Baumert