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Conclusions
•
Brain gliomas still represent a major challenge due to the
complexity of the medical management and impact on
patients’ life
•
The use of surgery, radiotherapy and chemotherapy need
to be tailored according to histology and molecular biology
as well as the clinical situation
•
Trials are ongoing in the attempt to answer relevant open
questions, as are the correct sequence/combination of
chemo-radiotherapy in some particular tumor subtypes
and the role of biologic targeted agents