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Heart and lung interaction
Heart irradiation
Cardiac damage /
perivascular fibrosis
Left ventricle diastolic dysfunction
Lung irradiation
Pulmonary vascular
remodeling
Classical signs of radiation pneumonitis:
Dyspnea, Inflammation, Fibrosis
Pulmonary
hypertension
L
R
Ghobadi et al. Int J Radiat Oncol Biol Phys. 2012