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CLINICAL TESTING

Screening test

Diagnostic test

Purpose

Reveal potential disease indicators

Establish presence of disease

Population

Large numbers potentially at risk

individuals (no symptoms)

Symptomatic individuals or positive

screening test

Method

Simple and acceptable

justifiable to establish diagnosis

Positive result

Suspicion of disease

Definitive diagnosis

Positive result threshold

High sensitivity: not to miss potential

disease

High specificity

Cost

Cheap, benefits should justify the costs

Higher costs justified