1652-1653 / 1676
Full model
Final model
b)
Hazard ratio (95% CI)
p-value
c)
Hazard ratio (95% CI)
p-value
C)
Mean dose to the heart [Gy]
1·015 (1·006–1·024)
0·001
1·015 (1·006–1·024)
0·001
Mean dose to the left internal carotid artery [Gy]
1·007 (0·991–1·023)
0·4
*
Mean dose to the right internal carotid artery [Gy]
0·997 (0·983–1·012)
0·7
*
Cumulative dose of anthracycline [50 mg/m
2
]
1·074 (1·013–1·138)
0·02
1·077 (1·021–1·137)
0·006
Cumulative dose of vinblastine [mg/m
2
]
1·000 (0·998–1·002)
0·8
*
Cumulative dose of vincristine [mg/m
2
]
0·989 (0·966–1·013)
0·4
*
1
1.5
2
2.5
3
0
100
200
300
400
500
1
1.5
2
2.5
3
0
5
10
15
20
25
30
35
40
Hazard ratio
A
Increase in mean heart dose (Gy)
Increase in cumulative dose of anthracyclines (mg/m
2
)
Hazard ratio
B