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Endpoints of treatment efficacy
Endpoint
Definition of event
Local control
No evidence of disease at the primary site (T-position)
Local failure rate
Recurrence in T-position
Locoregional control
No evidence of disease in T- and N-position
(Overall) survival
Death irrespective of cause
Cause-specific survival
Death of cancer
Disease-free survival
Any recurrence or death from any cause, whichever comes first
Local recurrence-free survival
Local recurrence or death from any cause, whichever comes first
Disease-free rate
Any recurrence
Local relapse free rate
Local recurrence
Bentzen et al. Radiotherapy Oncology 1998; 46: 5-18