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Langendijk et al. J Clin Oncol 2008;26:3770-3776

Clinical relevance xerostomia

Quality of life scale

Toxicity grading

P-value

Grade

0

Grade

1

Grade

2

Grade

3-4

Physical functioning

81

82

75

71

P-0.001

Role functioning

74

74

67

67

P=0.044

Emotional functioning

84

80

74

69

P=0.001

Social functioning

88

85

79

64

P<0.001

Global quality of life

73

75

65

55

P<0.001

Fatigue

25

28

36

42

P<0.001

Little effect

Moderate effect

Strong effect