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Prospective cohort study
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Advantages:
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Better control inclusion and exclusion criteria
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Predefined and consistent definitions of candidate
predictors
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Predefined and consistent assessment of endpoints:
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Fixed time points including baseline assessment
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Additional guidelines/training for “difficult” assessments
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Additional diagnostic procedures
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Predefined guidelines for radiotherapy:
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e.g. OAR delineation / fractionation / treatment planning
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Permits quality assurance programs