427 / 1109
Physical optimisations
Limitations
Quadratic dose difference may not reflect clinical objective
Properly ranking plans based on dose-volume objectives may fail
Objective: 50% of volume is to receive <50 G
y
Score: Plan 1:
10
/100
×
(
100 – 50
)
2
= 250
Plan 2:
50
/100
×
(
60 – 50
)
2
= 50
Result: Plan 1 is rejected!
Courtesy of Aswin Hoffmann