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Estimated sum of range uncertainties: ~3 - 5%

Range uncertainties are likely to be systematic.

Energy

(statistic)

Patient positioning

(statistic)

Inherent CT uncertainties, e.g

beam hardening, calibration

(systematic)

Distal end RBE enhancements (systematic)

CT artifacts (systematic)

Changes in patient anatomy (systematic & statistic)

Increase of potential magnitude

Adapted from Lomax T.

(AAPM Summer School

2015)

Range uncertainty