Prostate RT – Organs at risk + FLAME constraints
Organ at risk
Toxicity
Dose constraint
Rectum
Radiation proctitis, e.g. increased
bowel frequention, cramps, blood /
mucus discharge, diarrhea, use of
pads
V72 Gy < 5%
V50 Gy < 50%
Bladder, urethra
Radiation cystitis, e.g. increase in
urinary frequency, nocturia, dysuria,
hematuria
V80 Gy < cc
V72 Gy < 10%
V50 Gy < 50%
Anal sphincter
Pain, incontinence
Dmean < 37 Gy
Skin
Radiation dermatitis
ALARA