Recommendations for IMRT use
1) If the
reduction of xerostomia
and improved quality of
life are the main outcomes of interest, then
IMRT
is the
recommended
treatment
2) If
blindness
is to be minimized or avoided,
IMRT
is
indicated
in the definitive or adjuvant radiotherapy setting for nasal and
paranasal sinus cancers
3) If
osteoradionecrosis
is to be minimized or avoided,
IMRT
is
indicated
in the definitive or adjuvant radio- therapy of
tumours in the oral cavity, oropharynx, paranasal sinuses and
nasopharynx
4) If
treatment-related outcomes
(local control, overall
survival) are the main outcomes of interest, there are
no randomized
data to support or refute a recommendation of IMRT
over two-
or three-dimensional EBRT in any head and neck site
O’Sullivan, B., Rumble, R. B., & Warde, P. (2012). Intensity-modulated Radiotherapy in
the Treatment of Head and Neck Cancer. Clinical Oncology, 24(7), 474–487