OMB Meeting Book - January 8, 2015 - page 35

DESCRIPTION OF AOAC STATISTICS COMMITTEE GENERATED DOCUMENTS
ALTERNATIVE APROAC
H
ES FOR MULTI‐LAB STUD
Y
DOCUMNTS.   
Alternative approaches approved by Committee on Statistics and by OMB. 
1.
*tr322‐SAIS‐XXXV‐Reproducibility‐from‐PT‐data.pdf: Discussion on how 
to obtain reproducibility from proficiency test data, and the issues 
involved. 
……………………………… 
2
2.
tr333‐SAIS‐XLII‐guidelines‐for‐use‐of‐PT‐data.pdf: Recommended use 
of proficiency test data for estimating repeatability and reproducibility. ……………………………… 
8
3.
*tr324‐SAIS‐XXXVII‐Incremental‐collaborative‐studies.pdf: Proposed 
incremental collaborative studies to find repeatability and 
reproducibility via a sequential series of experiments. 
……………………………...
11
4.
tr326‐SAIS‐XXXIX‐Min‐degr‐freed‐for‐random‐factor‐estimation.pdf: 
The relationship of number of replicates or number of collaborators to 
precision of standard deviation for repeatability or reproducibility. 
……………………………… 
19
5.
tr323‐SAIS‐XXXVI‐When‐robust‐statistics‐make‐sense.pdf: Caveats and 
recommendations on the use of so‐called ‘robust’ statistics in 
accreditation studies. 
……………………………… 
21
TRADITIONAL PATHWAY MULTI‐LAB STUDY DOCUMENTS AND INSTRUMENTS.     
Traditional study approach spreadsheet remaining as part of acceptable approaches. 
6.
JAOAC 2006 89.3.797_Foster_Lee1.pdf: Journal article by Foster and 
Lee on the number of collaborators needed to estimate accurately a 
relative standard deviation for reproducibility. 
……………………………… 
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7.
LCFMPNCalculator.exe: This program analyzes serial dilution assay data 
to obtain a most probable number estimate of concentration with 
confidence interval. 
Separate Program
8.
AOAC_BlindDup_v2‐1.xls: This workbook analyzes multi‐collaborative 
study data with up to 4 replicates and reports all necessary statistics 
concerning repeatability and reproducibility for quantitative studies. 
Separate Program
9.
AOAC‐binary‐v2‐3.xls: This workbook analyzes multi‐collaborative 
study data with arbitrary number of replicates and reports all 
necessary statistics, including POD, repeatability and reproducibility 
with confidence intervals, for binary (presence/absence) qualitative 
studies. 
Separate Program
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