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11
C-methionine
– marker of proteine synthesis
– based on increased cellular proliferation in tumour cells
showing increased amino acid transport
– > brain tumors
•
11
C-acetate
– marker of lipid metabolism
– based on increased fatty acid synthesis in tumour cells
showing overexpression of fatty acid synthase
– very similar to
11
C-choline (also few urinary excretion)
•
68
Ga-PSMA
Glycoprotein with enzymatic function
(NAAG to glutamate & NAA)
–
– marker of lipid metabolism
– based on increased fatty acid synthesis in tumour cells
GV
showing overexpression of fatty acid synthase