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Rectum
(Topographic changes with DVH parameters)
:
Telangiectasia
: corresponded to the 2cm
3
high-dose rectal volume.
Ulcerations
: limited to the small high-dose volumes of 0.1cm
3
at the anterior rectal
wall segment.
Bladder:
The 5% incidence is observed at dose ranges from 60 to 70 Gy,
independently of the DVH parameter.
In contrast, as in the rectum, the doses for 10% and 20% complication rates are
l
l d d t
th DVH
t
d i
ith d
i
l
c ear y epen en on e
parame er an ncrease w ecreas ng vo ume.
This confirms that the 3D dose-volume parameters describe the dose effect in the
urinary bladder very well.
Sigmoid, colon:
When the commonly used institutional dose constraints for
OARs are not fulfilled the expected risk of side effects can be estimated based on
,
the dose response curves. Useful limits for D2 cc to the sigmoid and rectum not
including the contents (70-75 Gy)
P Georg et al Int J Radiation Oncology Biol Phys 2012; 82(2): 653–657
.
. .
.
.,