• Dose rate ≥ 0.5 Gy/h
• Treated surface ≥ 8 cm
2
or > 12 cm
2
• Catheter spacing ≥ 15 mm
• Total dose of exclusive brachytherapy ≥ 65 Gy
• Total dose of EBI + brachytherapy > 80 Gy
Pernot et al :
Radiother Oncol 1995;35:177–185
IJROBP 1994;29:973–679
Mazeron et al :
IJROBP 1990;18:1299–1306
IJROBP 1990;19:281–285
Radiother Oncol 1991 ;21:38–47
• Lead protection of the mandible
Mobile Tongue
Prognostic factors for late complications