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How much dose?

SINGLE FRACTION HDR BOOST

N.

patients

Gy per

fraction

Local

failure

Follow

-up y.

% good

Cosmesis

Resch

2002

Viena

274 7-12

3.9%

10

38

Neumanova 2008

Brno

215 8-12

1.5%

5

86

Hammer

1994

Linz

212

10

4.6%

5

78

Knauerhase 2008

Rostock

75 8-12

5.9%

10

78

Budrukkar

2007

Bombay

153

10

8%

10

83

Lopez

2009

Madrid

210

7

6%

10 86-96

Guinot. IVO 2012

Valencia

84

7

4.4%

10

92.5

BARTELINK 2007

2661 16Gy 6.2% 10

Be careful with cosmesis