820 / 1609
RISK GROUPS FOR BOOST
LOW RISK
INTERMEDIATE RISK
HIGH RISK
MEET ALL CRITERIA
MEET ANY CRITERIA
MEET ANY CRITERIA
Age >50
Age > 50 and one factor: Positive margins
Size ≤ 3cm
- Size > 3cm
Age ≤ 40 and one factor
No triple negative
- Triple negative
- triple negative
Clear margins ≥ 2mm
- close margins <2mm
- close margins <2mm
EIC -
- EIC+
- EIC +
LVI -
- LVI +
pN 0 (sentinel orALND)
- positive axilary nodes *
Unicentric and unifocal
- Multicentric/multifocal
- after neoadjuvant
therapy with residual tu
Age >40 < 50
Age ≤ 40 without major
risk criteria
BOOST NOT NEEDED
BOOST 10-16Gy
BOOST ≥ 16 Gy
* In case of pN+ with ≤3 positive nodes, age >60 and no other risk factors to omit the boost is justifiable.
GEC-ESTRO Breast working group