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Vaidya JS et al. Risk adapted targeted intra-operative

radiotherapy vs WBRT 5-year local control and OS from

the TARGIT-A randomised trial. Lancet 2014; 383:603-13

2014

Results APBI with intrabeam

1721 TARGIT (15% of TARGIT received WBI)

1730 WBI

Bad results are related to unadequate

localization of tumor bed

3.3%

vs

1.3%