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Dose volume response

5%

7%

3%

- Cox regression

- Dose and volume continous co-variates

- Significance:

p=0.07 for CTV

HR

D90

p=0.01 for CTV

HR

volume

- Hazard ratios:

0.962 for CTV

HR

D90 (per Gy)

1.018 for CTV

HR

volume (per cc)

Local control at 3 years

6%