•
A dose of at least 25 Gy is required to provide optimal local control
and minimize the rate of local failures in OAML
(Uno et al. 2003; Ejima et al. 2006; Tsang et al. 2003)
•
No differences in local or distal recurrence and survival after radiation
with less than or equal to 34 Gy compared with higher doses
(Le et al. 2002)
•
Significant ophthalmologic toxicity with vision loss after doses of
more than or equal to 34 Gy
(Le et al. 2002)
Considerations on RT dose