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Toxicity
o
Immediate toxicity consists of mild to moderate cutaneous or
conjunctival reactions
o
Long-term complications are observed in up to 50% of patients
o
The complications are relatively minor and include cataract
formation (30-50%) and mild xerophthalmia (20-40%)
o
RT doses above 36 Gy may result in deleterious ophthalmologic
toxicity such as ischemic retinopathy, optic atrophy, corneal
ulceration, neovascular glaucoma, associated with significant vision
loss