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Primary diffuse large B-cell lymphoma of the breast:

a study by the International Extranodal Lymphoma Study Group

Ryan et al, Ann Oncol 2008

Treatment

No of pts

%

Surgery only

11

5

RT only

14

7

CT only

31

15

S + RT

15

7

S + CT

32

16

RT + CT

59

29

S + RT + CT

42

21

Any surgery

100

49

Any RT

130

64

Any CT

164

80

Initially involved breast only: 50%

Initially involved breast + regional

lymph nodes: 35%

Median RT dose: 40 Gy

Range RT dose: 4-60 Gy