1351 / 1498
CR rate
R-B
R-CHOP/
R-CVP
Ratio
P
(s
Evaluable, IRC
31%
25%
1.25 (0.93–1.73)
0.0225
Randomized, IRC NHL
27%
23%
1.16 (0.81–1.65)
0.1289
Randomized IRC MCL
51%
24%
1.95 (1.01–3.77)
0.0180
Flinn et al ASH 2012
Untreated indolent or MCL
(n=447)
R-Bendamustine
(n=178)
R-CHOP/R-CVP
(n=206)
The BRIGHT STUDY
Powered for
non-inferiority in
CR rate