1397 / 1498
•
Rx:
mostly lytic lesions
a mixture of permeative, moth-eaten or destructive patterns of the bone cortex
often reactive changes of the periosteum
•
contrast-enhanced CT scan:
demonstrates the boundaries of any extraosseous extension
indicates cortical breakthrough by the tumour
detects osteolysis, osteosclerosis and fragments of bone sequestra
•
MRI:
more detailed extension of disease
evidence of cortical changes, intratumoural fibrosis, replacement of trabecular bone
and bone marrow by tumour
•
PET-CT:
recommended for initial evaluation, staging and response assessment
Radiographic findings