MHC
T Cell Receptor
Antigen
B7.1
/
CD80
B7.2
/
CD86
CD28
CTLA-4
/
CD152
B7DC
/
PDL2
/ CD273
B7H1
/
PD-L1
/ CD274
B7-H4
/ B7X / B7S1 / VTCN1
GITRL
/ AITRL / TNFSF18
B7-H3
/ CD276
OX40L
/ gp34 / CD252
CD137L
/
4-1BBL
/ TNFSF9
PD-1
/
PDCD1
/
CD279
?
?
GITR
/ AITR / TNFRSF18
?
OX40
/ ACT-135 / TNFRSF4 / CD134
CD137
/
4-1BB
/ ILA / TNFRSF9
T Cell
Antigen
Presenting Cell
ICOSL
/ B7H2 / GL50 / B7RP1 / CD275
ICOS
/ CD278/ AILIM / CRP-1
LAG-3
/ CD223
Understanding T- cell Immune Check-Points in the Tumour
Microenvironment and Reversing Immunosuppression
Inhibitory receptors
Activatory receptors