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Cumulative incidence any SMN by period

Cumulative incidence

40 yrs after HL: 48.5%

Schaapveld et al , submitted

0.0

10.0

20.0

30.0

40.0

50.0

Cumulative incidence of any SMN (%)

0 5 10 15 20 25 30 35 40 45

Follow-up time in years

1965-1976

1977-1988

1989-2000

sHR: 0.79 (95%CI 0.65-0.95)

1990-2000 versus 1965-1979

adjusted for age & gender

follow-up<20years

P

-trend:

0.015

Cumulative incidence of any SMN (%)