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Clinical target volume (CTV) (ICRU 83)

Volume of tissue that contains a demonstrable GTV and/or subclinical

malignant disease with a certain probability of occurrence considered

relevant for therapy

Encompasses the original (before any treatment) lymphoma (pre-chemo

GTV), modified to account for anatomic changes if treated with

chemotherapy up front

Normal structures (e.g., lungs, kidneys, muscles) that were clearly

uninvolved should be excluded

Residual lymphoma (post-chemo GTV) is always part of the CTV