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GHSG HD10, HD11 (CMT) Comparison

with NCIC CTG HD.6 (ABVD alone)

Endpoint

GHSG

HD10/11

NCIC CTG

HD.6

HR

95% CI

8-yr PFS

89%

86%

0.71

0.42-1.18

8- yr OS

95%

95%

1.09

0.49-2.40

8-yr TTP

93%

87%

0.44

0.24-0.78

# ABVD

2-4 (2.5)

4-6 (~5)

from Hay AE

et al., ASH Abstract 2012;548