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PET-adapted therapy with BV followed by augICE

Weekly BV x 2 cycles (6 doses)

Augmented ICE x2

cycles

Further treatment

according to treating

physician

HDT/ASCT

PET

+

-

PET

-

+

Summary

:

45 patients enrolled

27% PET negative after BV

alone (avoided ICE)

76% PET negative after whole

treatment program

All but 1 patient proceeded

to ASCT

Pre-ASCT RT

Pre-ASCT RT