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Is radiotherapy curative for stage I and II low-grade follicular
lymphoma?
Should RT alone remain standard of care ?
• US lymphocare 206 of 471 patients stage 1 follicular lymphoma
“rigorously staged” - Treatments given
– R-chemo (28%)
– RT (27%)
– Observation (17%)
– Systemic + RT (13%),
– rituximab monotherapy (12%), and other (3%).
• Median follow-up of 57 months, 44 (21%) progression events. PFS
significantly improved with either R-chemo or systemic and RT. No
differences in OS. (Friedberg J et al JCO 2012)