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Conventional chemo

BEACOPP baseline

CHOP-14, BEACOPP-14

BEACOPP escalated

weeks

0 2

4

6

8 10 12 14

0

3

6

9

12

15

18

21

weeks

0

3

6

9

12

15

18

21

weeks

weeks

0

4

8

12

16

20

24

28

Dose-intensification strategies

for first-line Lymphoma treatment