Implications
•
Salvage RT is an
option
in
localized
refractory / relapsed
DLBCL:
–
Definitive salvage in transplant ineligible pts
–
Additional treatment for transplant eligible pts
•
Use of RT
in salvage chemotherapy / transplant
trials
should
be controlled for.
•
Remaining questions:
–
Can
Dose escalation
improve outcome of Refractory or Resistant
disease?
–
Does higher
tumor volume
require higher dose?
–
What is the
size
of ref/rel
population
that could be salvaged by RT?