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Case-control study on cerebrovascular diseases following childhood

cancer : France, UK, the Netherlands

253 cases of permanent stroke and 253 individually matched controls

72 cases and 72 controls from the UK, from the BCCSS (UB, UK, M

Hawkins)

153cases and 153 controls, from the FCCSS (INSERM, France, F de

Vathaire).

28 cases and 28 controls from the DOG Later cohort (AMD, The

Netherlands, AMD, L Kremer)

Matching criteria

Cohort

Gender

Age at first primary cancer diagnosis (+/- 1 year)

Calendar year at first primary cancer diagnosis (+/- 3 years)

Length of follow-up

A control can serve as a control for more than one case. In addition,

control from one matched set may later be found to be a case, at which

point the appropriate control will be selected for the new set.