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Evidence for a Developmental Hypothesis for Childhood
Cancer
Scotting Perilongo & Walker
Nature Reviews Cancer (2005) 5; 481-488
•
Fidelity of Embryonic / Fetal / Immature
Cell Tissue
microenvironment
•
Teratocarcinomas
Mimic many tissues. If transplanted back into growing
embryos revert to normal cell behaviour
(Martin 1981, Andrews 2002)