194 / 1708
Ependymoma – international data / „infants“
Author, year
Pat.
RT
Survival
Grill et al., 2001
73 Chx only / RT at PD
4 y PFS : 26%/ 4 y. OS : 59%
(23% without RT)
Grundy et al.,
2007
89 Chx. only
RT at PD
M0 EFS OS
3 y 47.6 79.3%
5 y 41.8% 63.4%
Fouladi et al., 2009
21 Planned RT
< 18 mon : 48Gy
18-30 mon. :51 Gy
> 30 mon. : 54 Gy
5 y PFS : 33%
5 y. OS : 62%
Massimino et al.,
41 Chx. only / RT at PD
5 y PFS : 26%/ 5 y. OS : 37%
Merchant et al., 2009
78 RT only
5 y EFS : 68.6%/ OS : 80.4%
Grundy et al., 2010
11 Chx. only / RT at PD
1 y PFS : 1/11/ 1 y. OS : 9.1%
Timmermann et al.,
2004
HIT 88-89/91
34 RT : 21
No RT : 13
3 year PFS : 23.3%
3 year OS
RT : 66.7%/ no RT : 38.5%
HIT 2000
51 R0 : 61
R+ : 25
5 year PFS
R0 : 84.3 / R+ : 63.5%
Intracranial ependymoma