228 / 1708
HIT 2000: EFS - EP
°
II+
°
III
>4 years
/
R 0 versus R +
survival
R+: > 4 years
5 y EFS : 53.2 %
7 y EFS : 47.6 %
n = 43, 22 relapses
R0: 5 y EFS : 69.6 % 7 y EFS : 68.7 %
n = 138, 44 relapses
p = 0.009
years
survival
R+ disease has
negative impact
on EFS!