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Hippocampus

Composed of the dentate gyrus and cornu ammonis regions

Part of limbic system

Limbic system function: cooperation in learning,

consolidation and retrieval of information; essential for

formation of new memories

Bilateral and unilateral radiation injury of the hippocampus

alters learning and memory formation

Mean doses of >45G to left temporal lobe associated with

significant declines in longitudinal IQ