paediatrics Brussels 17

Lymphnode involvement in

Hodgkin`s disease:

•

Supradiaphgramatic lymphadenopathy

(cervical +++) :

80% of HD cases ; usually non inflammatory, painless,

ferm, sometimes tender

Mauch, Cancer 1993;71:2062

•

Mediastinal involvement

(leading to symptoms : dyspnea, cough, …) :

> 50% of HD cases (up to 75% of HD)

–

1/3 if < 10 y.

–

> 2/3 if adolescents

–

Rarely isolated (< 5%)

Crnkovich, JCO 1987:5(7)1041

•

isolated infradiaphragmatic

involvement : < 5%