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Rhabdomyosarcoma

Accounts for about 3-4% of malignant disease in children < 15

years

Most common soft tissue sarcoma in children

Annual incidence of RMS is 4.4 per million in white children

and 1.3 per million in black children

A small proportion associated with genetic conditions (Li-

Fraumeni syndrome, NF-1, Beckwith-Wiedemann syndrome)