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Use of Cone Down Boost

30 patients with parameningeal

RMS

Prior to 1992, pre-chemo volume

treated to 45 – 59.4 Gy

After 1992, pre-chemo volume

treated to 30.6 – 40 Gy

followed by cone down boost

to 41.4 – 55.2 Gy

No difference in local control

between two time methods

Chen C et al. Int J Radiat Oncol Biol Phys 2003; 55:1294-99