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G1

G2

G3

JBJS 1998

Grade Percentage

Necrosis

Histologic Appearance

I

0-49

Little or no necrosis

II

50-89

Areas of acellular tumor osteoid

and/or fibrotic material

attribuitable to the effect of

chemotherapy, with other areas

of viable tumor

III

90-99

Predominant areas of acellular

tumor osteoid and/or fibrotic

material attribuitable to the

effect of chemotherapy, with

only scattered foci of viable

tumor cells

IV

100

No pathologic evidence of viable

tumor within the specimen

I

II

III

IV