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Surgery

Goal of surgery: clear margins of normal tissue around the

entire tumour (“adequate margins”)

Intralesional resection

Tumor opened during surgery, or surgical field contaminated,

or microscopic or macroscopic residual disease

Marginal resection

Tumor removed en bloc, however, resection throught the

pseudocapsule of the tumor; microscopic residual disease

likely

Wide resection

Tumor and its pseudocapsule removed en bloc, surrounded

by healthy tissue, within the tumor-bearing compartment

Radical resection

The whole tumor-bearing compartment removed en bloc

(e.g. above the knee amputation for a lower leg tumor)

Enneking classification of surgical intervention

Enneking et al., Clin Orthop Rel Res, 1980