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Multivariate NTCP model:
Selection of covariates:
Final model:
Parameters for clinical outcome: Salivary glands
Beetz I et al. Development of NTCP models for head and neck cancer patients treated with
three-dimensional conformal radiotherapy for xerostomia and sticky saliva: The role of
dosimetric and clinical factors. Radiother. Oncol. Volume 105, Issue 1, Pages 86–93.
X
e
NTCP
β
ˆ
1
1
−
+
=
=
X
β
ˆ
-5.27 + 0.066*mean dose parotid glands +
+ 0.05*age + 0.916*baseline xerostomia score
Baseline xerostomia score is a simple clinical evaluation before the treatment
(dummy covariate):
0
: no xerostomia
1
: a bit of xerostomia