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CIBT wrt PT: Some important differences for TP
Peculiarities of carbon ion RBE and implications
– RBE-dependence on dose
– Plan MUs not scalable any longer!
– RBE not constant: How to come up with a robust multi-
beam plan?
– SFU(B)D only applicable for single beam per fraction (NIRS)!
– D
RBE,LEM-I
≠ D
RBE,NIRS
, conversion of treatment
protocols needed! Is always approximate!
– Approximations and shortcomings in clinical RBE-
models
Fossati et al. (2012), PMB