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SBRT: wide use,

high heterogeneity

M. Guckenberger et al. JTO 2013:

n=582, 13 institutions, SBRT 1998 - 2011

6 · 5. September 2017

Number of

patients Percentage Median Minimum Maximum Time-

trend

Inter-

institutional

variability

Dose calculation algorithm

p<0.001 p<0.001

Type A

265

45.5

Type B

249

42.8

unknown

68

11.7

Number of SBRT fractions

582

3

1

20

0.02

p<0.001

Single fraction dose PTV

encomassing (Gy)

582

12.5

2.9

33.0

NS p<0.001

Total dose PTV encompassing (Gy)

582

37.5

12.0

64.0 p<0.001 p<0.001

Dose inhomogeneity (PTV

encompasing dose / Maximum PTV

dose) (%)

582

65

60

100

NS p<0.001

Total BED dose PTV encompassing

(Gy)

582

84.4

38.3

180.0 p<0.001 p<0.001